{"product_id":"ppig-polyclonal-antibody-bt-ap13258","title":"PPIG Polyclonal Antibody - BT-AP13258","description":"\u003cp\u003ePPIG Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13258-20, BT-AP13258-50, BT-AP13258-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.,enzyme regulation:Cyclosporin A (CsA)-sensitive.,PPIases accelerate the folding of proteins.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the cyclophilin-type PPIase family.,Contains 1 PPIase cyclophilin-type domain.,subcellular location:Colocalizes with RNA splicing factors at nuclear speckles.,subunit:Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.,tissue specificity:Ubiquitous.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PPIG\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Peptidyl-prolyl cis-trans isomerase G\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13427; Mouse: A2AR02; Rat: O55035\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Peptidyl-prolyl cis-trans isomerase G;PPIase G;Peptidyl-prolyl isomerase G;EC 5.2.1.8;CASP10;Clk-associating RS-cyclophilin;CARS-Cyp;CARS-cyclophilin;SR-cyclophilin;SR-cyp;SRcyp;C\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9360\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239295967411,"sku":"BT-AP13258-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239296000179,"sku":"BT-AP13258-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239296032947,"sku":"BT-AP13258-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d74d2573-c2c6-44c8-8ab9-5129f05e1af3.png?v=1769392672","url":"https:\/\/afsbio.com\/products\/ppig-polyclonal-antibody-bt-ap13258","provider":"AFSBio Inc.","version":"1.0","type":"link"}