{"product_id":"ppig-polyclonal-antibody-ra34198","title":"PPIG Polyclonal Antibody - RA34198","description":"\u003cp\u003ePPIG Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA34198-50, RA34198-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0) .,domain:The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.,enzyme regulation:Cyclosporin A (CsA) -sensitive.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Colocalizes with RNA splicing factors at nuclear speckles.,subunit:Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.,tissue specificity:Ubiquitous.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 9360\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 82\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q13427\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120589070515,"sku":"RA34198-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120589103283,"sku":"RA34198-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b27d12b9-8dd0-499a-a8a5-9418a13b0ed6.png?v=1773367893","url":"https:\/\/afsbio.com\/products\/ppig-polyclonal-antibody-ra34198","provider":"AFSBio Inc.","version":"1.0","type":"link"}