{"product_id":"ppm1b-polyclonal-antibody-e-ab-18930","title":"PPM1B Polyclonal Antibody - E-AB-18930","description":"\u003cp\u003ePPM1B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-18930-60, E-AB-18930-120, E-AB-18930-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PPM1B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MGC21657; OTTHUMP00000158953; OTTHUMP00000158954; OTTHUMP00000158955; OTTHUMP00000202394; OTTHUMP00000202395; OTTHUMP00000202399; PP2C beta; PP2C beta X; PP2C-beta; PP2CB; PP2Cbeta; PPC2BETAX; PPM 1B; Ppm1b; PPM1B; Protein phosphatase 1B (formerly 2C) magnesium dependent beta isoform; Protein phosphatase 1B; Protein phosphatase 1B magnesium dependent beta isoform; Protein phosphatase 2C beta isoform; Protein phosphatase 2C isoform beta; Protein phosphatase 2C like protein; Protein phosphatase; Mg2+\/Mn2+ dependent; 1B\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O75688\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the PP2C family of Ser\/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.72 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human PPM1B\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130727497907,"sku":"E-AB-18930-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130727530675,"sku":"E-AB-18930-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130727563443,"sku":"E-AB-18930-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8dd062cd-3a9e-4900-9dd0-e6eebffeb2a3.png?v=1709811872","url":"https:\/\/afsbio.com\/products\/ppm1b-polyclonal-antibody-e-ab-18930","provider":"AFSBio Inc.","version":"1.0","type":"link"}