{"product_id":"ppm1f-polyclonal-antibody-e-ab-16729","title":"PPM1F Polyclonal Antibody - E-AB-16729","description":"\u003cp\u003ePPM1F Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-16729-60, E-AB-16729-120, E-AB-16729-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PPM1F\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Ca(2+)\/calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; CAMKP; CaMKPase; FEM 2; hFEM-2; KIAA0015; Partner of PIX 2; POPX2; PP2C phosphatase; Ppm1f; PPM1F; Protein fem-2 homolog; Protein phosphatase 1F (PP2C domain containing); Protein phosphatase 1F; Protein phosphatase Mg2+\/Mn2+ dependent 1F\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P49593\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the PP2C family of Ser\/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium\/calmodulin-dependent protein kinase II gamma (CAMK2G\/CAMK-II) is found to be one of the substrates of this phosphatase.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.8 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human PPM1F\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 50kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143845281971,"sku":"E-AB-16729-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143845314739,"sku":"E-AB-16729-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143845347507,"sku":"E-AB-16729-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6f07cff6-24f1-48e1-92ae-9d40f15f0b11.png?v=1710242394","url":"https:\/\/afsbio.com\/products\/ppm1f-polyclonal-antibody-e-ab-16729","provider":"AFSBio Inc.","version":"1.0","type":"link"}