{"product_id":"ppme1-polyclonal-antibody-bt-ap13263","title":"PPME1 Polyclonal Antibody - BT-AP13263","description":"\u003cp\u003ePPME1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13263-20, BT-AP13263-50, BT-AP13263-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PPME1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Protein phosphatase methylesterase 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y570; Mouse: Q8BVQ5; Rat: Q4FZT2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Protein phosphatase methylesterase 1;PME-1;EC 3.1.1.89\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 51400\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239296262323,"sku":"BT-AP13263-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239296295091,"sku":"BT-AP13263-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239296327859,"sku":"BT-AP13263-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a288cc10-bf4c-4d9f-b05c-811a0aa64fe4.png?v=1769392677","url":"https:\/\/afsbio.com\/products\/ppme1-polyclonal-antibody-bt-ap13263","provider":"AFSBio Inc.","version":"1.0","type":"link"}