{"product_id":"ppp1r3c-polyclonal-antibody-e-ab-52884","title":"PPP1R3C Polyclonal Antibody - E-AB-52884","description":"\u003cp\u003ePPP1R3C Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-52884-60, E-AB-52884-120, E-AB-52884-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PPP1R3C\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: OTTHUMP00000020089; Phosphatase 1; regulatory inhibitor subunit 5; PP1 subunit R5; ppp1r3c; PPP1R5 ; PPR3C; Protein phosphatase 1 regulatory subunit 3C; Protein phosphatase 1 regulatory subunit 5; protein phosphatase 1; regulatory (inhibitor) subunit 3C; Protein targeting to glycogen; PTG; R5\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9UQK1\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.9 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human PPP1R3C\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133545447603,"sku":"E-AB-52884-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133545480371,"sku":"E-AB-52884-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133545513139,"sku":"E-AB-52884-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_861a2212-a462-4c54-aeeb-92d61df9f650.png?v=1709899864","url":"https:\/\/afsbio.com\/products\/ppp1r3c-polyclonal-antibody-e-ab-52884","provider":"AFSBio Inc.","version":"1.0","type":"link"}