{"product_id":"ppp2r3c-rabbit-pab-es3253","title":"PPP2R3C rabbit pAb - ES3253","description":"\u003cp\u003ePPP2R3C rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3253-50, ES3253-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a regulatory subunit of the serine\/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PPP2R3C; C14orf10; G5PR; Serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A\/6C\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PPP2R3C. AA range:165-214\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 55kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 55012\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q969Q6\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Cytoplasm. Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202124079283,"sku":"ES3253-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202124112051,"sku":"ES3253-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_269f67aa-a0f3-4a7f-94d6-c41d6eeb9256.png?v=1767122475","url":"https:\/\/afsbio.com\/products\/ppp2r3c-rabbit-pab-es3253","provider":"AFSBio Inc.","version":"1.0","type":"link"}