{"product_id":"ppp2r4-polyclonal-antibody-e-ab-60498","title":"PPP2R4 Polyclonal Antibody - E-AB-60498","description":"\u003cp\u003ePPP2R4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60498-60, E-AB-60498-120, E-AB-60498-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PPP2R4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PTPA; PP2A; PPP2R4; PR53\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q15257\u003c\/p\u003e\n\n\u003cp\u003eBackground: Protein phosphatase 2A is one of the four major Ser\/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B\/PR55, B'\/PR61, and B''\/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PPP2R4\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 31kDa\/33kDa\/36kDa\/40kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43144005550259,"sku":"E-AB-60498-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43144005583027,"sku":"E-AB-60498-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43144005615795,"sku":"E-AB-60498-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b3a0e847-ca49-42bc-b6e2-194c8e215d45.png?v=1710245114","url":"https:\/\/afsbio.com\/products\/ppp2r4-polyclonal-antibody-e-ab-60498","provider":"AFSBio Inc.","version":"1.0","type":"link"}