{"product_id":"pr-monoclonal-antibody-z15-bt-mca1059","title":"PR Monoclonal Antibody (Z15) - BT-MCA1059","description":"\u003cp\u003ePR Monoclonal Antibody (Z15)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA1059-20, BT-MCA1059-50, BT-MCA1059-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling; Signal Transduction; Neuroscience; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PGR\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Progesterone receptor\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P06401; Mouse: Q00175; Rat: Q63449\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5241\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240047042739,"sku":"BT-MCA1059-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240047075507,"sku":"BT-MCA1059-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240047108275,"sku":"BT-MCA1059-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_485c9b21-05b5-41dc-abe9-e13351a89b82.png?v=1769402646","url":"https:\/\/afsbio.com\/products\/pr-monoclonal-antibody-z15-bt-mca1059","provider":"AFSBio Inc.","version":"1.0","type":"link"}