{"product_id":"prc1-polyclonal-antibody-e-ab-61477","title":"PRC1 Polyclonal Antibody - E-AB-61477","description":"\u003cp\u003ePRC1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61477-60, E-AB-61477-120, E-AB-61477-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PRC1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PRC1; ASE1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O43663\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2\/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PRC1 (NP_003972.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IF \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 61kDa\/66kDa\/70kDa\/71kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 72kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146168041651,"sku":"E-AB-61477-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146168074419,"sku":"E-AB-61477-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146168107187,"sku":"E-AB-61477-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_db6ea8f7-080b-4251-843a-8481b6928363.png?v=1710291525","url":"https:\/\/afsbio.com\/products\/prc1-polyclonal-antibody-e-ab-61477","provider":"AFSBio Inc.","version":"1.0","type":"link"}