{"product_id":"prdm12-polyclonal-antibody-bs77450","title":"PRDM12 Polyclonal Antibody-BS77450","description":"PRDM12 Polyclonal Antibody\n\nSizes: 50µl, 100µl\n\nCatalogue Numbers:  BS77450-50, BS77450-100\n\nProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\n\nSwiss-Prot: Q9H4Q4\n\nHost: Rabbit\n\nReactivity: Human, Mouse\n\nApplications: WB\n\nAll Applications: WB,1:500 - 1:2000\n\nBackground: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]\n\nPurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\n\nSpecificity: Unmodification \n\nExtra Notes: Western blot analysis of extracts of U-87MG cells, using PRDM12 antibody at 1:1000 dilution.\nSecondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.\nLysates\/proteins: 25ug per lane.\nBlocking buffer: 3% nonfat dry milk in TBST.\nDetection: ECL Basic Kit.\nExposure time: 90s.\n\nNote: For research use only, not for use in diagnostic procedure.\n\nBioworld Molecular Weight: 45kDa\n\nAlternative Name: HSAN8; PFM9; PRDM12\n\nImmunogen: Recombinant fusion protein of human PRDM12(NP_067632.2).\n\nConjugate: Unconjugated\n\nModification: Unmodified ","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42924622414003,"sku":"BS77450-50","price":334.88,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42924622446771,"sku":"BS77450-100","price":576.38,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c4a777bb-dcec-434a-81fb-e74eee4c0b57.jpg?v=1703937241","url":"https:\/\/afsbio.com\/products\/prdm12-polyclonal-antibody-bs77450","provider":"AFSBio Inc.","version":"1.0","type":"link"}