{"product_id":"prkdc-monoclonal-antibody-bt-mca3152","title":"PRKDC Monoclonal Antibody - BT-MCA3152","description":"\u003cp\u003ePRKDC Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3152-50, BT-MCA3152-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine\/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PRKDC\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3H6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PRKDC\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PRKDC expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 46.9kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P78527\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HYRC, p350, DNAPK, DNPK1, HYRC1, XRCC7, DNA-PKcs, PRKDC\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5591\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238606659763,"sku":"BT-MCA3152-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238606692531,"sku":"BT-MCA3152-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9f61b5ce-a93b-4bfb-b9e6-4eafcdc5a6a8.png?v=1769383001","url":"https:\/\/afsbio.com\/products\/prkdc-monoclonal-antibody-bt-mca3152","provider":"AFSBio Inc.","version":"1.0","type":"link"}