{"product_id":"pro-glucagon-polyclonal-antibody-e-ab-93117","title":"Pro-glucagon Polyclonal Antibody - E-AB-93117","description":"\u003cp\u003ePro-glucagon Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93117-60, E-AB-93117-120, E-AB-93117-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Pro-glucagon\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GCG; GLP-1; GLP1; GLP2; GRPP; glucagon\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Developmental Biology, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P01275\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human Pro-glucagon\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 20kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 21kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146678337715,"sku":"E-AB-93117-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146678370483,"sku":"E-AB-93117-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146678403251,"sku":"E-AB-93117-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6c1f11d1-2e59-49cb-a13e-a2bad0820104.png?v=1710299962","url":"https:\/\/afsbio.com\/products\/pro-glucagon-polyclonal-antibody-e-ab-93117","provider":"AFSBio Inc.","version":"1.0","type":"link"}