{"product_id":"probetacellulin-polyclonal-antibody-bt-ap07405","title":"Probetacellulin Polyclonal Antibody - BT-AP07405","description":"\u003cp\u003eProbetacellulin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07405-20, BT-AP07405-50, BT-AP07405-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BTC encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of betacellulin bind to multiple different EGF receptors. Betacellulin romotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in BTC may be associated with type 2 diabetes in human patients.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BTC\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Probetacellulin Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 19746\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P35070; Mouse: Q05928\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BTC; Probetacellulin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 685\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239852990643,"sku":"BT-AP07405-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239853023411,"sku":"BT-AP07405-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239853056179,"sku":"BT-AP07405-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cfad0462-6a32-4c13-9188-126685c14fe6.png?v=1769399998","url":"https:\/\/afsbio.com\/products\/probetacellulin-polyclonal-antibody-bt-ap07405","provider":"AFSBio Inc.","version":"1.0","type":"link"}