{"product_id":"proc-light-chain-cleaved-leu179-rabbit-pab-es20045","title":"PROC (light chain, Cleaved-Leu179) rabbit pAb - ES20045","description":"\u003cp\u003ePROC (light chain, Cleaved-Leu179) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20045-50, ES20045-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Vitamin K-dependent protein C (EC 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide]\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 17 45kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5624\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P04070\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted. Golgi apparatus. Endoplasmic reticulum.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202426757299,"sku":"ES20045-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202426790067,"sku":"ES20045-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_5837c7d6-07d7-4bbf-b6fb-6f1fd286acda.png?v=1767128961","url":"https:\/\/afsbio.com\/products\/proc-light-chain-cleaved-leu179-rabbit-pab-es20045","provider":"AFSBio Inc.","version":"1.0","type":"link"}