{"product_id":"proprotein-convertase-9-pcsk9-polyclonal-antibody-bs71876","title":"Proprotein Convertase 9 (PCSK9) Polyclonal Antibody - BS71876","description":"\u003cp\u003eProprotein Convertase 9 (PCSK9) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS71876-50, BS71876-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regμlated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellμlar matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing resμlts in mμltiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IF\/ICC, IP\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PCSK9, FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human Proprotein Convertase 9(PCSK9)(NP_777596.2).\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB, 1:500 - 1:1000 IHC, 1:50 - 1:200 IF\/ICC, 1:50 - 1:200 IP, 1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Proprotein Convertase 9(PCSK9) polyclonal antibody detects endogenous levels of Proprotein Convertase 9(PCSK9) protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 80KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q8NBP7\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45939672416435,"sku":"BS71876-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45939672449203,"sku":"BS71876-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_41a3d5a7-cf33-4737-a858-16025b1d8d02.jpg?v=1788296283","url":"https:\/\/afsbio.com\/products\/proprotein-convertase-9-pcsk9-polyclonal-antibody-bs71876","provider":"AFSBio Inc.","version":"1.0","type":"link"}