{"product_id":"proteasome-alpha-6-monoclonal-antibody-mb11465","title":"Proteasome alpha 6 Monoclonal Antibody-MB11465","description":"\u003cp\u003eProteasome alpha 6 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB11465-50, MB11465-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P60900\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 27 kDa; Observed MW: 27 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Proteasome subunit alpha type 6 in K562, C6, 3T3, Hela lysates using Proteasome alpha 6 antibody., Immunocytochemistry analysis of Proteasome subunit alpha type 6 in Hela using Proteasome subunit alpha type 6 antibody, and DAPI\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: proteasome subunit alpha 6; IOTA; p27K; PROS27\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human Proteasome subunit alpha type 6\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42975250022579,"sku":"MB11465-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42975250088115,"sku":"MB11465-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_8e6c6a7d-f861-4ef2-b7ed-1afd66eb9eed.jpg?v=1705662290","url":"https:\/\/afsbio.com\/products\/proteasome-alpha-6-monoclonal-antibody-mb11465","provider":"AFSBio Inc.","version":"1.0","type":"link"}