{"product_id":"psap-monoclonal-antibody-bt-mca4158","title":"PSAP Monoclonal Antibody - BT-MCA4158","description":"\u003cp\u003ePSAP Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4158-50, BT-MCA4158-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PSAP\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3A5H7\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PSAP\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PSAP (AA: 17-216) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 58.1kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P07602\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GLBA, SAP1, SAP2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5660\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238404251827,"sku":"BT-MCA4158-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238404284595,"sku":"BT-MCA4158-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1b9dd717-63f6-4d98-9498-dc4de5f0680b.png?v=1769380108","url":"https:\/\/afsbio.com\/products\/psap-monoclonal-antibody-bt-mca4158","provider":"AFSBio Inc.","version":"1.0","type":"link"}