{"product_id":"psip1-polyclonal-antibody-bs71250","title":"PSIP1 Polyclonal Antibody-BS71250","description":"\u003cp\u003ePSIP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS71250-50, BS71250-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O75475\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000\u003cbr\u003e\nIHC\t1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The lens epithelium-derived growth factor (LEDGF), also designated p75p52, is a transcriptional coactivator that complexes with the human immunodeficiency virus type 1 (HIV-1) integrase. LEDGF\/p75p52 is essential for the nuclear localization and chromosomal association of viral proteins. As the primary integrase-to-chromatin tethering factor for HIV-1, LEDGF\/p75p52 is responsible for the cellular trafficking of lentiviral integrases. During apoptosis, LEDGF\/p75p52 is cleaved at three sites by caspase-3 and caspase-7, contributing to the pathogenesis of atopic disorders.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PSIP1 polyclonal antibody detects endogenous levels of PSIP1 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry of paraffin-embedded rat testis using PSIP1 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: p52; p75; PAIP; DFS70; LEDGF; PSIP2;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant protein of human PSIP1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923471536307,"sku":"BS71250-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923471569075,"sku":"BS71250-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f8735ed4-72ac-49cf-9e2f-1355d078eaf8.jpg?v=1703850094","url":"https:\/\/afsbio.com\/products\/psip1-polyclonal-antibody-bs71250","provider":"AFSBio Inc.","version":"1.0","type":"link"}