{"product_id":"psma6-polyclonal-antibody-e-ab-19189","title":"PSMA6 Polyclonal Antibody - E-AB-19189","description":"\u003cp\u003ePSMA6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19189-60, E-AB-19189-120, E-AB-19189-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PSMA6\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 27 kDa prosomal protein; IOTA; Macropain iota chain; Macropain subunit iota; MGC22756; MGC2333; MGC23846; Multicatalytic endopeptidase complex iota chain; p27K; PROS 27; PROS-27; PROS27; Prosomal P27K protein; Proteasome (prosome macropain) subunit alpha type 6; Proteasome iota chain; Proteasome subunit alpha type 6; Proteasome subunit alpha type-6; Proteasome subunit iota; PSA6; PSMA 6; PSMA6\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P60900\u003c\/p\u003e\n\n\u003cp\u003eBackground: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.56 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human PSMA6\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143914913971,"sku":"E-AB-19189-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143914946739,"sku":"E-AB-19189-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143914979507,"sku":"E-AB-19189-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_351ad470-c97c-4e3e-b5e7-39a4d5feaa1e.png?v=1710243619","url":"https:\/\/afsbio.com\/products\/psma6-polyclonal-antibody-e-ab-19189","provider":"AFSBio Inc.","version":"1.0","type":"link"}