{"product_id":"psmd1-rabbit-polyclonal-antibody-bt-ap04318","title":"PSMD1 Rabbit Polyclonal Antibody - BT-AP04318","description":"\u003cp\u003ePSMD1 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04318-20, BT-AP04318-50, BT-AP04318-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes| a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base| which contains 6 ATPase subunits and 2 non-ATPase subunits| and a lid| which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome| the immunoproteasome| is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid| which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PSMD1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PSMD1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q99460; Mouse: Q3TXS7; Rat: O88761\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PSMD1; 26S proteasome non-ATPase regulatory subunit 1; 26S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5707; Mouse: 70247; Rat: 83806\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239017177267,"sku":"BT-AP04318-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239017210035,"sku":"BT-AP04318-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239017242803,"sku":"BT-AP04318-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_69686dad-61ac-45de-866c-c47d3984ee9f.png?v=1769387982","url":"https:\/\/afsbio.com\/products\/psmd1-rabbit-polyclonal-antibody-bt-ap04318","provider":"AFSBio Inc.","version":"1.0","type":"link"}