{"product_id":"pth-pthrp-r-polyclonal-antibody-bt-ap07477","title":"PTH\/PTHrP-R Polyclonal Antibody - BT-AP07477","description":"\u003cp\u003ePTH\/PTHrP-R Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07477-20, BT-AP07477-50, BT-AP07477-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by PTH1R (parathyroid hormone 1 receptor) is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for PTH1R.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PTH1R\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PTH\/PTHrP-R Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 52979\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q03431; Mouse: P41593; Rat: P25961\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PTH1R; PTHR; PTHR1; Parathyroid hormone\/parathyroid hormone-related peptide receptor; PTH\/PTHrP type I receptor; PTH\/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5745; Mouse: 19228; Rat: 56813\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239858921651,"sku":"BT-AP07477-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239858954419,"sku":"BT-AP07477-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239858987187,"sku":"BT-AP07477-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b034634d-beff-438b-b3d6-2c95d947911b.png?v=1769400077","url":"https:\/\/afsbio.com\/products\/pth-pthrp-r-polyclonal-antibody-bt-ap07477","provider":"AFSBio Inc.","version":"1.0","type":"link"}