{"product_id":"pth-pthrp-r-rabbit-pab-es6897","title":"PTH\/PTHrP-R rabbit pAb - ES6897","description":"\u003cp\u003ePTH\/PTHrP-R rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES6897-50, ES6897-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PTH1R; PTHR; PTHR1; Parathyroid hormone\/parathyroid hormone-related peptide receptor; PTH\/PTHrP type I receptor; PTH\/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PTHR1. AA range:145-194\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 52kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5745\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q03431\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Multi-pass membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202319999155,"sku":"ES6897-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202320031923,"sku":"ES6897-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_2718a13f-217b-454f-b0eb-ec99b2dc43b6.png?v=1767126494","url":"https:\/\/afsbio.com\/products\/pth-pthrp-r-rabbit-pab-es6897","provider":"AFSBio Inc.","version":"1.0","type":"link"}