{"product_id":"ptn-polyclonal-antibody-bs7504","title":"PTN Polyclonal Antibody-BS7504","description":"\u003cp\u003ePTN Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7504-50, BS7504-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P21246\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000\u003cbr\u003e\nIHC\t1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Pleiotrophin (PTN) also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM) is a protein that in humans is encoded by the PTNgene. Pleiotrophin is an 18-kDa growth factor that has a high affinity for heparin. It is structurally related to midkine and retinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PTN polyclonal antibody detects endogenous levels of PTN protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~19 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot analysis of PTN polyclonal antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: HARP; \u003cbr\u003e\nHB-GAM; \u003cbr\u003e\nHBBM; \u003cbr\u003e\nHBGAM; \u003cbr\u003e\nHBGF-8; \u003cbr\u003e\nHBGF8; \u003cbr\u003e\nHBNF; \u003cbr\u003e\nHBNF-1; \u003cbr\u003e\nHBNF1; \u003cbr\u003e\nheparin affin regulatory protein; \u003cbr\u003e\nHeparin binding growth associated molecule; \u003cbr\u003e\nHeparin Binding Growth Factor 8; \u003cbr\u003e\nHeparin binding neurite outgrowth promoting factor 1; \u003cbr\u003e\nHeparin-binding brain mitogen; \u003cbr\u003e\nheparin-binding growth associated molecule; \u003cbr\u003e\nHeparin-binding growth factor 8; \u003cbr\u003e\nHeparin-binding growth-associated molecule; \u003cbr\u003e\nHeparin-binding neurite outgrowth-promoting factor 1; \u003cbr\u003e\nNEGF1; \u003cbr\u003e\nNeurite Growth Promoting Factor 1; \u003cbr\u003e\nNeurite outgrowth-promoting factor, heparin-binding; \u003cbr\u003e\nOSF-1; \u003cbr\u003e\nOSF1; \u003cbr\u003e\nOsteoblast-specific factor 1; \u003cbr\u003e\nosteoblast-specific factor; \u003cbr\u003e\npleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1); \u003cbr\u003e\nPleiotrophin; \u003cbr\u003e\nPTN; \u003cbr\u003e\nPTN_HUMAN;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant full length Human PTN.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923511218355,"sku":"BS7504-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923511251123,"sku":"BS7504-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_b657758c-259c-4a4a-a056-9a3df7a09acd.jpg?v=1703850797","url":"https:\/\/afsbio.com\/products\/ptn-polyclonal-antibody-bs7504","provider":"AFSBio Inc.","version":"1.0","type":"link"}