{"product_id":"ptpα-phospho-tyr798-rabbit-pab-es6938","title":"PTPα (phospho Tyr798) rabbit pAb - ES6938","description":"\u003cp\u003ePTPα (phospho Tyr798) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES6938-50, ES6938-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PTPRA; PTPA; PTPRL2; Receptor-type tyrosine-protein phosphatase alpha; Protein-tyrosine phosphatase alpha; R-PTP-alpha\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Monkey\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PTPRA around the phosphorylation site of Tyr798. AA range:753-802\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 100 90kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5786\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P18433\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Localizes to focal adhesion sites following integrin engagement.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202322161843,"sku":"ES6938-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202322194611,"sku":"ES6938-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_4322a26f-7674-4e63-8af7-6e470c84b02d.png?v=1767126548","url":"https:\/\/afsbio.com\/products\/ptp%ce%b1-phospho-tyr798-rabbit-pab-es6938","provider":"AFSBio Inc.","version":"1.0","type":"link"}