{"product_id":"ptpa-polyclonal-antibody-e-ab-19232","title":"PTPA Polyclonal Antibody - E-AB-19232","description":"\u003cp\u003ePTPA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19232-60, E-AB-19232-120, E-AB-19232-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PTPA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: subunit B''; KIAA0044 ; MGC2184 ; Phosphotyrosyl phosphatase activator; PP2A; PP2A phosphatase activator ; PP2A subunit B'; PP2A subunit B' isoform PR53; PP2A subunit B' PR53 isoform ; PPP2R4; PR53 ; PR53 isoform; Protein phosphatase 2; regulatory subunit B-prime; Protein phosphatase 2A activator regulatory subunit 4; Protein phosphatase 2A regulatory subunit B' (PR 53); PTPA; PTPA; Serine\/threonine protein phosphatase 2A regulatory subunit B' ; Serine\/threonine-protein phosphatase 2A activator; Serine\/threonine-protein phosphatase 2A regulatory subunit 4; Serine\/threonine-protein phosphatase 2A regulatory subunit B''\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q15257\u003c\/p\u003e\n\n\u003cp\u003eBackground: Protein phosphatase 2A is one of the four major Ser\/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B\/PR55, B'\/PR61, and B''\/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.84 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human PTPA\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:100, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133392126131,"sku":"E-AB-19232-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133392158899,"sku":"E-AB-19232-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133392191667,"sku":"E-AB-19232-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_84ebff89-60e3-41d1-a095-f3d43993a6ec.png?v=1709898409","url":"https:\/\/afsbio.com\/products\/ptpa-polyclonal-antibody-e-ab-19232","provider":"AFSBio Inc.","version":"1.0","type":"link"}