{"product_id":"ptprf-polyclonal-antibody-bt-ap13396","title":"PTPRF Polyclonal Antibody - BT-AP13396","description":"\u003cp\u003ePTPRF Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13396-20, BT-AP13396-50, BT-AP13396-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pat\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Signal transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PTPRF\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Receptor-type tyrosine-protein phosphatase F\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P10586; Mouse: A2A8L5; Rat: Q64604\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Receptor-type tyrosine-protein phosphatase F;EC 3.1.3.48;Leukocyte common antigen related;LAR\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5792\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239301865651,"sku":"BT-AP13396-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239301898419,"sku":"BT-AP13396-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239301931187,"sku":"BT-AP13396-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b7fac0f2-afe4-4cfb-8e05-65ac7176e354.png?v=1769392763","url":"https:\/\/afsbio.com\/products\/ptprf-polyclonal-antibody-bt-ap13396","provider":"AFSBio Inc.","version":"1.0","type":"link"}