{"product_id":"pu-1-polyclonal-antibody-bt-ap07509","title":"PU.1 Polyclonal Antibody - BT-AP07509","description":"\u003cp\u003ePU.1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07509-20, BT-AP07509-50, BT-AP07509-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. Spi-1 proto-oncogene can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this SPI1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SPI1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PU.1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31083\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P17947; Mouse: P17433; Rat: Q6BDS1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SPI1; Transcription factor PU.1; 31 kDa-transforming protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6688; Mouse: 20375; Rat: 366126\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239860134067,"sku":"BT-AP07509-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239860166835,"sku":"BT-AP07509-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239860199603,"sku":"BT-AP07509-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5db49cee-b7fc-4a01-8dc4-ca5ae1864575.png?v=1769400092","url":"https:\/\/afsbio.com\/products\/pu-1-polyclonal-antibody-bt-ap07509","provider":"AFSBio Inc.","version":"1.0","type":"link"}