{"product_id":"pum1-polyclonal-antibody-e-ab-62320","title":"PUM1 Polyclonal Antibody - E-AB-62320","description":"\u003cp\u003ePUM1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62320-60, E-AB-62320-120, E-AB-62320-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PUM1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PUM1; HSPUM; PUMH; PUMH1; PUML1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Epigenetics and Nuclear Signaling,Developmental Biology,Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q14671\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PUM1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000, IF 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 119kDa\/124kDa\/126kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 135kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146238066867,"sku":"E-AB-62320-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146238099635,"sku":"E-AB-62320-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146238132403,"sku":"E-AB-62320-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_bb443c10-9ace-4670-b995-391abf7a43e8.png?v=1710292164","url":"https:\/\/afsbio.com\/products\/pum1-polyclonal-antibody-e-ab-62320","provider":"AFSBio Inc.","version":"1.0","type":"link"}