{"product_id":"puma-monoclonal-antibody-mb11483","title":"PUMA Monoclonal Antibody-MB11483","description":"\u003cp\u003ePUMA Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB11483-50, MB11483-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9BXH1\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Essential mediator of p53\/TP53-dependent and p53\/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53\/TP53. Regulates ER stress-induced neuronal apoptosis.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 21 kDa; Observed MW: 21 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunocytochemistry analysis of PUMA in 293T using PUMA antibody, and DAPI., Western blot analysis of PUMA in K562 lysates using PUMA antibody., Western blot analysis of PUMA in Jurkat, THP-1, C6, 3T3, Hela lysates using PUMA antibody, Immunohistochemistry analysis of paraffin-embedded Human breast cancer using PUMA antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: BBC3; PUMA; Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human PUMA\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43055908847795,"sku":"MB11483-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43055908880563,"sku":"MB11483-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1429ed39-3a2b-4cac-853e-a5e788e5b73a.jpg?v=1708086534","url":"https:\/\/afsbio.com\/products\/puma-monoclonal-antibody-mb11483","provider":"AFSBio Inc.","version":"1.0","type":"link"}