{"product_id":"pura-polyclonal-antibody-bt-ap13411","title":"PURA Polyclonal Antibody - BT-AP13411","description":"\u003cp\u003ePURA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13411-20, BT-AP13411-50, BT-AP13411-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PURA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Transcriptional activator protein Pur-alpha\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q00577; Mouse: P42669; Rat: P86252\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Transcriptional activator protein Pur-alpha;Purine-rich single-stranded DNA-binding protein alpha\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5813\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239302815923,"sku":"BT-AP13411-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239302848691,"sku":"BT-AP13411-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239302881459,"sku":"BT-AP13411-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2d80b8a8-026d-49cb-98a8-33b1eaba5be4.png?v=1769392778","url":"https:\/\/afsbio.com\/products\/pura-polyclonal-antibody-bt-ap13411","provider":"AFSBio Inc.","version":"1.0","type":"link"}