{"product_id":"purified-anti-human-cd47-antibody-cc2c6d4-e-ab-f1060a","title":"Purified Anti-Human CD47 Antibody [CC2C6D4] - E-AB-F1060A","description":"\u003cp\u003ePurified Anti-Human CD47 Antibody [CC2C6D4]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F1060A-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD47\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Leukocyte surface antigen CD47, Cd47, Integrin-associated protein, IAP,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: CC2C6D4\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q08722\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51\/CD61, CD41\/CD61. Thrombospondin is a ligand for CD47, in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09793A\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 961\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43157341307059,"sku":"E-AB-F1060A-100","price":151.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_30d7ae55-38e1-47b0-96d3-7336b65057c4.png?v=1710513686","url":"https:\/\/afsbio.com\/products\/purified-anti-human-cd47-antibody-cc2c6d4-e-ab-f1060a","provider":"AFSBio Inc.","version":"1.0","type":"link"}