{"product_id":"purified-anti-human-cd86-antibody-bu63-e-ab-f1012a","title":"Purified Anti-Human CD86 Antibody [BU63] - E-AB-F1012A","description":"\u003cp\u003ePurified Anti-Human CD86 Antibody [BU63]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F1012A-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD86\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: T-lymphocyte activation antigen CD86, Cd86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM, Block\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: BU63\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P42081\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes\/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09793A\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 942\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43157317353651,"sku":"E-AB-F1012A-100","price":224.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d86566bc-1044-4ec8-acf6-30ca796dc411.png?v=1710513411","url":"https:\/\/afsbio.com\/products\/purified-anti-human-cd86-antibody-bu63-e-ab-f1012a","provider":"AFSBio Inc.","version":"1.0","type":"link"}