{"product_id":"r-spondin-monoclonal-antibody-ra11956","title":"R-Spondin Monoclonal Antibody - RA11956","description":"\u003cp\u003eR-Spondin Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11956-50, RA11956-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: R-spondin 1 (RSPO1) Homo sapiens This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 284654\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q2MKA7\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118995398835,"sku":"RA11956-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118995431603,"sku":"RA11956-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_264bc5fc-6f6a-40bc-8702-7bcd5ef189b6.png?v=1773344045","url":"https:\/\/afsbio.com\/products\/r-spondin-monoclonal-antibody-ra11956","provider":"AFSBio Inc.","version":"1.0","type":"link"}