{"product_id":"r4rl2-rabbit-pab-es11214","title":"R4RL2 rabbit pAb - ES11214","description":"\u003cp\u003eR4RL2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11214-50, ES11214-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system., PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein., similarity:Belongs to the Nogo receptor family., similarity:Contains 8 LRR (leucine-rich) repeats., subcellular location:Localized to the surface of neurons, including axons., tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.,\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein . at AA range: 290-370\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 46kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 349667\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q86UN3\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Cell projection, dendrite. Perikaryon. Cell projection, axon. Localized to the surface of neurons, including axons. Detected close to synapses, but is excluded from synapses.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201753309363,"sku":"ES11214-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201753342131,"sku":"ES11214-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_522a4886-ec3b-4c44-be35-c734339ceeb9.png?v=1767111019","url":"https:\/\/afsbio.com\/products\/r4rl2-rabbit-pab-es11214","provider":"AFSBio Inc.","version":"1.0","type":"link"}