{"product_id":"rab-5c-a153-polyclonal-antibody-bs3919","title":"Rab 5C (A153) Polyclonal Antibody-BS3919","description":"\u003cp\u003eRab 5C (A153) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3919-50, BS3919-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P51148\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral\/Rec and Rho\/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles.\u003c\/p\u003e \n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Rab 5C (A153) polyclonal antibody detects endogenous levels of Rab 5C protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Rab 5C (A153) pAb at 1:1000 dilution\u003cbr\u003e\nLane 1: A375 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: Hela whole cell lysate (30ug)\u003cbr\u003e\nLane 3: The Lung tissue lysate of Rat (40ug)\u003cbr\u003e\nLane 4: The Lung tissue lysate of Mouse (40ug), Immunohistochemistry (IHC) analyzes of Rab 5C (A153) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 24 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: RAB; member of RAS oncogene family like; \u003cbr\u003e\nRAB5C; \u003cbr\u003e\nRAB5C; member of RAS oncogene family; \u003cbr\u003e\nRAB5C; member RAS oncogene family; \u003cbr\u003e\nRAB5C; \u003cbr\u003e\nRAB5CL; \u003cbr\u003e\nRAB5L; \u003cbr\u003e\nRABL; \u003cbr\u003e\nRas-related protein Rab-5C;\u003c\/p\u003e \n\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human Rab 5C.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953241362611,"sku":"BS3919-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953241395379,"sku":"BS3919-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c68fce2c-b67c-48ee-93de-a93eb033975f.jpg?v=1705057497","url":"https:\/\/afsbio.com\/products\/rab-5c-a153-polyclonal-antibody-bs3919","provider":"AFSBio Inc.","version":"1.0","type":"link"}