{"product_id":"rab3ip-polyclonal-antibody-e-ab-63202","title":"RAB3IP Polyclonal Antibody - E-AB-63202","description":"\u003cp\u003eRAB3IP Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63202-60, E-AB-63202-120, E-AB-63202-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RAB3IP\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RAB3IP; RABIN3; RABIN8\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q96QF0\u003c\/p\u003e\n\n\u003cp\u003eBackground: Guanine nucleotide exchange factor (GEF which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS, apical surface formation and lumenogenesis.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RAB3IP\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28kDa\/33-53kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 53kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146280337587,"sku":"E-AB-63202-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146280370355,"sku":"E-AB-63202-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146280403123,"sku":"E-AB-63202-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5f9f8202-bf4a-49c0-88c0-47c1bdbc82dd.png?v=1710292934","url":"https:\/\/afsbio.com\/products\/rab3ip-polyclonal-antibody-e-ab-63202","provider":"AFSBio Inc.","version":"1.0","type":"link"}