{"product_id":"rac1-cdc42-phospho-ser71-rabbit-polyclonal-antibody-bt-ap12225","title":"Rac1\/cdc42 (Phospho-Ser71) Rabbit Polyclonal Antibody - BT-AP12225","description":"\u003cp\u003eRac1\/cdc42 (Phospho-Ser71) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12225-20, BT-AP12225-50, BT-AP12225-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a small GTPase of the Rho-subfamily| which regulates signaling pathways that control diverse cellular functions including cell morphology| migration| endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42| and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP)| which subsequently activates Arp2\/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3| 4| 5| 7| 8 and 20.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Immunology; Cancer\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Rac1\/cdc42\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P60953; Mouse: P60766; Rat: Q8CFN2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Rac1\/cdc42;Ser71; Cell division control protein 42 homolog; G25K GTP-binding protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 998; Mouse: 12540; Rat: 64465\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238926049459,"sku":"BT-AP12225-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238926082227,"sku":"BT-AP12225-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238926114995,"sku":"BT-AP12225-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a5213fcb-8a00-4e2d-9167-edbb810833e7.png?v=1769386781","url":"https:\/\/afsbio.com\/products\/rac1-cdc42-phospho-ser71-rabbit-polyclonal-antibody-bt-ap12225","provider":"AFSBio Inc.","version":"1.0","type":"link"}