{"product_id":"rad18-phospho-ser403-rabbit-polyclonal-antibody-bt-ap12227","title":"Rad18 (Phospho-Ser403) Rabbit Polyclonal Antibody - BT-AP12227","description":"\u003cp\u003eRad18 (Phospho-Ser403) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12227-20, BT-AP12227-50, BT-AP12227-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6| which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart| this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RAD18\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Rad18\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NS91; Mouse: Q9QXK2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Rad18;Ser403; E3 ubiquitin-protein ligase RAD18; EC 6.3.2.-; Postreplication repair protein RAD18; hHR18; hRAD18; RING finger protein 73\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 56852; Mouse: 58186\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239017373875,"sku":"BT-AP12227-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239017406643,"sku":"BT-AP12227-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239017439411,"sku":"BT-AP12227-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a3a18201-111e-45e0-9f20-07a44c9d90e0.png?v=1769387984","url":"https:\/\/afsbio.com\/products\/rad18-phospho-ser403-rabbit-polyclonal-antibody-bt-ap12227","provider":"AFSBio Inc.","version":"1.0","type":"link"}