{"product_id":"rae1-polyclonal-antibody-e-ab-61318","title":"RAE1 Polyclonal Antibody - E-AB-61318","description":"\u003cp\u003eRAE1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61318-60, E-AB-61318-120, E-AB-61318-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RAE1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RAE1; MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Cell Biology,Epigenetics and Nuclear Signaling,Signal Transduction,Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P78406\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RAE1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 40kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146160472243,"sku":"E-AB-61318-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146160505011,"sku":"E-AB-61318-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146160537779,"sku":"E-AB-61318-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_23f6213a-455c-4d19-a504-bb9a5536f8fe.png?v=1710291390","url":"https:\/\/afsbio.com\/products\/rae1-polyclonal-antibody-e-ab-61318","provider":"AFSBio Inc.","version":"1.0","type":"link"}