{"product_id":"rank-rabbit-pab-es8652","title":"RANK rabbit pAb - ES8652","description":"\u003cp\u003eRANK rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8652-50, ES8652-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8\/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; CD antigen CD265)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide from human protein at AA range: 60-120\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 66kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 8792\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9Y6Q6\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform RANK-e5a]: Cell membrane; Single-pass type I membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202389762227,"sku":"ES8652-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202389794995,"sku":"ES8652-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_c7aa5d98-007f-4557-a8ea-f7dadaba8d38.png?v=1767128095","url":"https:\/\/afsbio.com\/products\/rank-rabbit-pab-es8652","provider":"AFSBio Inc.","version":"1.0","type":"link"}