{"product_id":"rap1a-polyclonal-antibody-e-ab-13927","title":"RAP1A Polyclonal Antibody - E-AB-13927","description":"\u003cp\u003eRAP1A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-13927-60, E-AB-13927-120, E-AB-13927-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RAP1A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: C21KG; G-22K; GTP-binding protein smg p21A; KREV1; RAP1A; RAP1A; member of RAS oncogene family; RAP1A; Ras-related protein 1A; Ras-related protein Krev-1; Ras-related protein Rap-1A; SMGP21\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P62834\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human RAP1A\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124140540083,"sku":"E-AB-13927-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124140572851,"sku":"E-AB-13927-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124140605619,"sku":"E-AB-13927-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2ea5a7e2-d67e-48a7-b150-86c9f029b042.png?v=1709724581","url":"https:\/\/afsbio.com\/products\/rap1a-polyclonal-antibody-e-ab-13927","provider":"AFSBio Inc.","version":"1.0","type":"link"}