{"product_id":"rasa4-polyclonal-antibody-e-ab-93002","title":"RASA4 Polyclonal Antibody - E-AB-93002","description":"\u003cp\u003eRASA4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93002-60, E-AB-93002-120, E-AB-93002-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RASA4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RASA4; CAPRI; GAPL\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O43374\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras\/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RASA4\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 85kDa\/90kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146668507315,"sku":"E-AB-93002-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146668540083,"sku":"E-AB-93002-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146668572851,"sku":"E-AB-93002-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_fe3caf03-11fd-4721-b870-7ccb37a211aa.png?v=1710299754","url":"https:\/\/afsbio.com\/products\/rasa4-polyclonal-antibody-e-ab-93002","provider":"AFSBio Inc.","version":"1.0","type":"link"}