{"product_id":"rassf1-polyclonal-antibody-e-ab-60249","title":"RASSF1 Polyclonal Antibody - E-AB-60249","description":"\u003cp\u003eRASSF1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60249-60, E-AB-60249-120, E-AB-60249-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RASSF1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RASSF1; 123F2; NORE2A; RASSF1A; RDA32; REH3P21\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Epigenetics and Nuclear Signaling,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9NS23\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RASSF1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 8kDa\/9kDa\/16kDa\/21kDa\/31kDa\/38kDa\/39kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 39kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146045587635,"sku":"E-AB-60249-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146045620403,"sku":"E-AB-60249-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146045653171,"sku":"E-AB-60249-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_840545d9-7ec9-4e6d-b34c-d92ed6327ebc.png?v=1710290532","url":"https:\/\/afsbio.com\/products\/rassf1-polyclonal-antibody-e-ab-60249","provider":"AFSBio Inc.","version":"1.0","type":"link"}