{"product_id":"rassf8-polyclonal-antibody-bs62455","title":"RASSF8 Polyclonal Antibody-BS62455","description":"\u003cp\u003eRASSF8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62455-50, BS62455-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q8NHQ8\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB:1:500~1:1000\u003c\/p\u003e \n\n\u003cp\u003eBackground: RASSF8 (Ras association (RalGDS\/AF-6 or RA) domain (N-terminal) family member 8), also known as HoJ-1 (carcinoma-associated protein HoJ-1), is an evolutionarily conserved member of the N-terminal RASSF family which is also comprised of RASSF7, PAMCI (or RASSF9) and RASSF10. RASSF8 contains an N-terminal RA domain and is believed to participate in the Ras signaling pathway. A reciprocal chromosomal translocation involving the genes encoding RASSF8 and Fibulin-1 is associated with a complex form of synpolydactyly, a condition in which there are typically more than five digits on a hand or foot and patients exhibit webbing or fusion of fingers and toes. In addition, RASSF8 is capable of acting as a tumor suppressor in lung cancer, as is suggested by the ectopic expression of RASSF8 inhibiting anchorageindependent growth. This implies that the loss of functional RASSF8 may be implicated in the development of lung cancer.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The protein was purified from E.coli and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: RASSF8 polyclonal antibody detects endogenous levels of RASSF8 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of RASSF8 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLaneA:The testis tissue lysate of Rat\u003cbr\u003e\nLaneB:The testis tissue lysate of Mouse\u003cbr\u003e\nLaneC:Hela whole cell lysate\u003cbr\u003e\nLaneD:L02 whole cell lysate\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 45,48 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1; RASSF8; C12orf2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human RASSF8.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910459363507,"sku":"BS62455-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910459396275,"sku":"BS62455-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0fe653d1-4c02-49d1-a81c-4b6218dc134c.jpg?v=1703092828","url":"https:\/\/afsbio.com\/products\/rassf8-polyclonal-antibody-bs62455","provider":"AFSBio Inc.","version":"1.0","type":"link"}