{"product_id":"rassf8-rabbit-polyclonal-antibody-es3830","title":"RASSF8 Rabbit Polyclonal Antibody - ES3830","description":"\u003cp\u003eRASSF8 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3830-50, ES3830-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12, 22)(p11.2, q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: RASSF8, C12orf2, Ras association domain-containing protein 8, Carcinoma-associated protein HOJ-1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from RASSF8. at AA range: 60-140\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: RASSF8\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: RASSF8 Polyclonal Antibody detects endogenous levels of RASSF8 protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Widely expressed as a 6,2 kb transcript, A 2,2 kb alternatively spliced transcript is expressed exclusively in testis,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 48kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Disease: A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly, also referred to as 3\/3-prime\/4 synpolydactyly associated with metacarpal and metatarsal synostoses [MIM: 608180]. Reciprocal translocation t(12, 22)(p11.2, q13.3) with FBLN1\u003cbr\u003e\nSimilarity: Contains 1 Ras-associating domain\u003cbr\u003e\nTissue Specificity: Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis\u003c\/p\u003e\n\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: RASSF8\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Ras association domain-containing protein 8\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q8CJ96\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46316507693235,"sku":"ES3830-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46316507726003,"sku":"ES3830-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/rassf8-rabbit-polyclonal-antibody-es3830","provider":"AFSBio Inc.","version":"1.0","type":"link"}