{"product_id":"rb-polyclonal-antibody-bz16670","title":"Rb Polyclonal Antibody-BZ16670","description":"\u003cp\u003eRb Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16670-50, BZ16670-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P06400\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4\/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK\/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 106 kDa; Observed MW: 106 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Retinoblastoma in Jurkat lysates; MCF-7 lysates using Rb antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Retinoblastoma antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of Rb in SH-SY5Y using Retinoblastoma antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Retinoblastoma\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993842978995,"sku":"BZ16670-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993843011763,"sku":"BZ16670-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_45155599-70fe-459c-8e00-b4876719cf3f.jpg?v=1706184168","url":"https:\/\/afsbio.com\/products\/rb-polyclonal-antibody-bz16670","provider":"AFSBio Inc.","version":"1.0","type":"link"}