{"product_id":"rb33b-polyclonal-antibody-bt-ap13610","title":"RB33B Polyclonal Antibody - BT-AP13610","description":"\u003cp\u003eRB33B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13610-20, BT-AP13610-50, BT-AP13610-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by this gene is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Tags and cell markers\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: RAB33B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Ras-related protein Rab-33B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H082; Mouse: O35963\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Ras-related protein Rab-33B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 83452\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239309303987,"sku":"BT-AP13610-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239309336755,"sku":"BT-AP13610-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239309369523,"sku":"BT-AP13610-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c68d4e7b-8b0a-4758-9111-2c2c81fb0014.png?v=1769392870","url":"https:\/\/afsbio.com\/products\/rb33b-polyclonal-antibody-bt-ap13610","provider":"AFSBio Inc.","version":"1.0","type":"link"}