{"product_id":"rb40c-polyclonal-antibody-bt-ap13614","title":"RB40C Polyclonal Antibody - BT-AP13614","description":"\u003cp\u003eRB40C Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13614-20, BT-AP13614-50, BT-AP13614-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,Belongs to the small GTPase superfamily. Rab family.,Contains 1 SOCS box domain.,subunit:Component of the probable SCF-like ECS(RAB40C) E3 ubiquitin-protein ligase complex which contains CUL5, RNF7\/RBX2, Elongin BC complex and RAB40C. Interacts with CUL5, RNF7, TCEB1 and TCEB2.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RAB40C\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Ras-related protein Rab-40C\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96S21; Mouse: Q8VHQ4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Ras-related protein Rab-40C;Rar-like protein;Ras-like protein family member 8C;SOCS box-containing protein RAR3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 57799\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239309598899,"sku":"BT-AP13614-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239309631667,"sku":"BT-AP13614-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239309664435,"sku":"BT-AP13614-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_49373182-f3e2-409d-b3d7-e1d972df93a7.png?v=1769392875","url":"https:\/\/afsbio.com\/products\/rb40c-polyclonal-antibody-bt-ap13614","provider":"AFSBio Inc.","version":"1.0","type":"link"}