{"product_id":"rbfox1-polyclonal-antibody-e-ab-92804","title":"RBFOX1 Polyclonal Antibody - E-AB-92804","description":"\u003cp\u003eRBFOX1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92804-60, E-AB-92804-120, E-AB-92804-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RBFOX1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RBFOX1; 2BP1; A2BP1; FOX-1; FOX1; HRNBP1\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9NWB1\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RBFOX1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:100-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 40kDa\/42kDa\/44kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 45-50KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43145965076659,"sku":"E-AB-92804-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43145965109427,"sku":"E-AB-92804-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43145965142195,"sku":"E-AB-92804-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_bd50e1fa-e1a2-4288-b1db-6bf1f77ca0f9.png?v=1710288944","url":"https:\/\/afsbio.com\/products\/rbfox1-polyclonal-antibody-e-ab-92804","provider":"AFSBio Inc.","version":"1.0","type":"link"}